Doxorubicin and liposomal doxorubicin affect microRNA expression in rat right ventricles
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| Rok publikování | 2014 |
| Druh | Konferenční abstrakty |
| Citace | |
| Popis | In order to better understand the acute effects of doxorubicin (DOX) and liposomal DOX on the heart, analysis of 4 selected microRNAs (miR-208a/146a/216b/let-7g) that may be involved in DOX-induced cardiotoxicity was performed, both in the left and right ventricles of the Wistar rat exposed to one dose of DOX/liposomal DOX. This acute administration of mentioned drugs affects stightly expression of selected microRNAs, especially in right ventricle. |
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