Droplet microfluidics in (bio)chemical analysis

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Publikace nespadá pod Filozofickou fakultu, ale pod Středoevropský technologický institut. Oficiální stránka publikace je na webu muni.cz.
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BASOVA Evgenia FORET František

Rok publikování 2015
Druh Článek v odborném periodiku
Časopis / Zdroj Analyst
Fakulta / Pracoviště MU

Středoevropský technologický institut

Citace
www http://pubs.rsc.org/en/content/articlepdf/2015/an/c4an01209g
Doi http://dx.doi.org/10.1039/c4an01209g
Obor Analytická chemie, separace
Klíčová slova Droplet chemistry; microfluidics; single cell; compartmentalization; encapsulation
Popis Droplet microfluidics may soon change the paradigm of performing chemical analyses and related instrumentation. It can improve not only the analysis scale, possibility for sensitivity improvement, and reduced consumption of chemical and biological reagents, but also the speed of performing a variety of unit operations. At present, microfluidic platforms can reproducibly generate monodisperse droplet populations at kHz or higher rates with droplet sizes suitable for high-throughput experiments, singlecell detection or even single molecule analysis. In addition to being used as microreactors with volume in the micro- to femtoliter range, droplet based systems have also been used to directly synthesize particles and encapsulate biological entities for biomedicine and biotechnology applications. This minireview summarizes various droplet microfluidics operations and applications for (bio)chemical assays described in the literature during the past few years.
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