Biomacromolecular structure quality – improvement or stagnation?

Varování

Publikace nespadá pod Filozofickou fakultu, ale pod Přírodovědeckou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	HORSKÝ Vladimír BENDOVÁ Veronika SVOBODOVÁ VAŘEKOVÁ Radka KOČA Jaroslav
Rok publikování	2017
Druh	Další prezentace na konferencích
Fakulta / Pracoviště MU	Přírodovědecká fakulta
Citace
Popis	We have performed wide scale analysis of trends in quality and size of biomacromolecules and their ligands. 70 diverse factors have been considered. Information about structures and their quality have been obtained from the Protein Data Bank, while the state of ligand quality has been sourced by our database ValidatorDB. Existence of some discovered trends was expected (e.g., newer structures have better quality). Other trends surprised us (e.g., ligand quality is stagnant at best, currently utilised structure validation methods do not validate ligands well). Discovered trends are openly available in the ValTrendsDB database.
Související projekty:	Statistické a deterministické modelování