Assessing Freezing of Gait in Parkinson's Disease Using Analysis of Hypokinetic Dysarthria

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Publikace nespadá pod Filozofickou fakultu, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.
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GALÁŽ Zoltán MEKYSKA Jiří KISKA Tomáš ZVONČÁK Vojtěch MUCHA Ján SMÉKAL Zdeněk ELIÁŠOVÁ Ilona MRAČKOVÁ Martina KOŠŤÁLOVÁ Milena REKTOROVÁ Irena FAUNDEZ-ZANUY Marcos

Rok publikování 2017
Druh Článek ve sborníku
Konference 40th Anniversary of International Conference on Telecommunications and Signal Processing (TSP)
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www http://ieeexplore.ieee.org/document/8076085/
Doi http://dx.doi.org/10.1109/TSP.2017.8076085
Obor Neurologie, neurochirurgie, neurovědy
Klíčová slova acoustic analysis; freeying of gait; hypokinetic dysarthria; Parkinson’s disease; regression
Popis Hypokinetic dysarthria (HD) and freezing of gait (FOG) are frequent symptoms of Parkinson's disease (PD). The aim of this work is to reveal pathological mechanisms common for HD and FOG, and use acoustic analysis of dysarthric speech to assess the gait difficulties in PD. We used a correlation analysis to investigate a relationship between speech features and FOG evaluated by freezing of gait questionnaire (FOG-Q). We found speech features quantifying reduced mobility of the articulatory organs significantly correlated with all parts of the questionnaire. Next, we built multivariate regression models to estimate the FOG-Q total score. With this approach, mean estimation error rate of 14.71% was achieved. We confirmed the previous findings of a close relationship between HD and FOG in PD. Furthermore, we showed it is possible to accurately (with the error of approximately 0.5 points) estimate FOG-Q using a reasonable number of conventional speech features.
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