Baroreflex sensitivity and body growth parameters in children and adolescents
| Autoři | |
|---|---|
| Rok publikování | 2001 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Experimental and Clinical Cardiology |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Fyziologie |
| Klíčová slova | Age; Baroreflex sensitivity; Growth; Height; Spectral analysis; Weight. |
| Popis | OBJECTIVE:To determine the relationship between the baroreflex sensitivity expressed in ms/mmHg (BRS) and in Hz/mmHg (BRSf) and the body growth parameters. METHODS: Two hundred and one children and adolescents aged 10-21 years were examined. This population was analysed as a whole and subsequently was divided into 2 groups: group A - normotensive control (healthy, number of subjects n=154), group B - children with systolic casual blood pressure on primary diagnosis was > 140 mmHg (in 3 measurements at least one week apart, n=47). These groups were divided into subgroups according to the age. BRS and BRSf were determined by spectral analysis of blood pressure and pulse interval variability (5 minute records by Finapres, metronome controlled breathing at frequency of 0.33 Hz). The parameters of body growth (body height, weight, body mass index - BMI) were assessed. Correlation coefficient (Spearman) was calculated between pairs of all parameters (age, pulse interval - PI, BRS, BRSf, height, weight, BMI) for the whole group, groups A, B and for subgroups related to the age. RESULTS: BRS did not correlate with age; it correlated with PI in whole population, in groups A,B and also in age-related subgroups. BRS correlated only exceptionally either with weight, height and/or BMI in the oldest followed subjects (aged 17-19), but there was no correlation with the groups A,B and also with the whole study population. BRSf correlated significantly (p<0.01) with age. It was pulse interval independent for group A and also age-related subgroups. BRSf correlated with weight, height, BMI for normotensive group and for whole population, but not for age-related subgroups. CONCLUSION: BRS (which is mean pulse interval related parameter) does not correlate with age. On the contrary, BRSf (which is mean pulse interval independent) decreases with age significantly. Significant relationship between BRSf and parameters of body growth is related to the age. |
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