Intramolecular 1,3-Dipolar Cycloaddition Initiated by Microwaves
| Autoři | |
|---|---|
| Rok publikování | 2001 |
| Druh | Článek ve sborníku |
| Konference | Proceedings - 18th International Congres of Heterocyclic Chemistry |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Organická chemie |
| Klíčová slova | Microwaves; 1;3-Dipolar Cycloaddition; Intramolecular cycloaddition |
| Popis | In our experiments we concentrated on application of azomethine ylides stabilized by carbonyl in intramolecular cycloaddition reaction under microwave irradiation. Thus, aromatic aldehydes with gama-double bond in ortho-position bound chain afforded in the presence of secondary amine fused heterocyclic compounds.We tried to compare some of the known reactions carried at classical heating with newly substituted substrates in order to follow influence of substitution upon the reaction. Application of microwaves represents a new field of reaction conditions improvement as well as a way of compounds preparation in higher yield and shorter time comparatively with classical conditions and sometimes is very close to so called "green chemistry" when working without solvents. |
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