Statistical approach in search for optimal signal in simple olfactory neuronal models
| Název česky | Statistický přístup ke hledání optimálního signálu v jednoduchých modelech čichového neuronu |
|---|---|
| Autoři | |
| Rok publikování | 2008 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Mathematical Biosciences |
| Fakulta / Pracoviště MU | |
| Citace | |
| www | doi:10.1016/j.mbs.2008.02.010 |
| Obor | Teorie informace |
| Klíčová slova | Fisher information; Olfactory neuron; Optimal signal |
| Popis | Several models (concentration detectors and a flux detector) for coding of odor intensity in olfactory sensory neurons are investigated. Behavior of the system is described by different stochastic processes of binding the odorant molecules to the receptors and their activation. Characteristics how well the odorant concentration can be estimated from the knowledge of response, the number of activated neurons, are studied. The approach is based on the Fisher information and analogous measures. These measures of optimality are computed and applied to locate the odorant concentration which is most suitable for coding. The results are compared with the classical deterministic approach which judges the optimal odorant concentration via steepness of the input-output function. |
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