Effect of sequential frontotemporal repetitive transcranial magnetic stimulation (rTMS) on schizophrenia
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Rok publikování | 2010 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | Activitas Nervosa Superior Rediviva |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Psychiatrie, sexuologie |
Klíčová slova | CSP; frontotemporal; rTMS; schizophrenia; stimulation |
Popis | Modulation of the symptoms of schizophrenia, with the exception of the auditory hallucinations, by rTMS requires a new stimulation paradigm. Unipolar, left-sided, sequential fronto-temporal rTMS produce a significant reduction in all schizophrenia symptoms, especially the positive ones. A reduction in schizophrenic psychopathology was associated with prolongation of the CSP period, which can be assessed as an objective marker of reactivity. Since dual stimulation was well tolerated, it represents an alternative stimulation paradigm for treatment of schizophrenia. Complete verification will require a larger patient population sample, and preferably a double-blind study protocol. Unipolar, left side, sequential fronto-temporal rTMS caused alleviation of the symptoms of schizophrenia and was well tolerated. Therefore it may represent a new alternative therapy for schizophrenic patients. |
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