Informace o projektu
Structural characterization of phage assembly and genome packaging in bacterial cells
(PhageAssembly)
- Kód projektu
- 1233487
- Období řešení
- 7/2023 - 6/2025
- Investor / Programový rámec / typ projektu
-
Evropská unie
- Horizont Evropa
- Akce Marie Skłodowska-Curie (MSCA)
- Fakulta / Pracoviště MU
- Středoevropský technologický institut
Staphylococcus aureus stands out among the opportunistic human pathogens because of causing a variety of diseases and a wide potential for acquiring antimicrobial resistance. Due to the spread of methicillin- and vancomycin-resistant strains combined with the ability of biofilm formation that drastically complicates the treatment, this microorganism obtained high priority in the World Health Organisation list of pathogens for the research and development of new treatment approaches.
The research project is aimed to study the phage infection cycle in near-native conditions at high-resolution in situ. Such structural analysis of phage replication is needed for phage introduction as a therapeutic agent and may contribute to the development of more efficient approaches in phage therapy.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 1
2023
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BACTERIOPHAGE PHI812 HEAD ASSEMBLY IN THE CELLS OF STAPHYLOCOCCUS AUREUS
Rok: 2023, druh: Konferenční abstrakty