The role of different 5-HT2 receptor ligands in the mediation of methamphetamine reward properties
| Autoři | |
|---|---|
| Rok publikování | 2003 |
| Druh | Článek v odborném periodiku |
| Časopis / Zdroj | Behavioural Pharmacology |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Farmakologie a lékárnická chemie |
| Klíčová slova | 5-HT2 receptor ligands; methamphetamine; reward properties |
| Popis | Our results indicate that only non-selective blockade of 5-HT2A/2B/2C receptors leaded to suppression of rat methamphetamine intake while their stimulation produced no changes. These data correspond with other findings that 5-HT2 receptor antagonists attenuate the expression of alcohol and opiate withdrawal syndrome, and also diminish discriminative-stimulus effects of d-amphetamine. |
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