Project information
Dynamika a organizace chromosomů během buněčného cyklu a při diferenciaci v normě a patologii
- Project Identification
- GBP302/12/G157 (kod CEP: GBP302/12/G157)
- Project Period
- 1/2012 - 12/2018
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Projects to promote excellence in basic research
- MU Faculty or unit
- Faculty of Informatics
- Other MU Faculty/Unit
- Faculty of Medicine
- Cooperating Organization
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Institute of Biophysics
- Responsible person doc. RNDr. Stanislav Kozubek, DrSc.
- Responsible person doc. RNDr. Dušan Cmarko, Ph.D.
- Responsible person prof. RNDr. Ivan Raška, DrSc.
Projekt excelence navazuje na podobně pojmenovaný úspěěný projekt Centra základního výzkumu LC535 a propojí nejlepší české týmy zabývající se uspořádáním a funkcí jádra buňky a epigenetikou buněk zdravých i nádorových, v normě i při poškození.
Publications
Total number of publications: 121
2019
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Automatic Fusion of Segmentation and Tracking Labels
Computer Vision – ECCV 2018 Workshops, year: 2019
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Biomechanical Characterization of Human Pluripotent Stem Cell-Derived Cardiomyocytes by Use of Atomic Force Microscopy
Atomic Force Microscopy, year: 2019, number of pages: 11 s.
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Distinct cellular responses to replication stress leading to apoptosis or senescence
FEBS Open Bio, year: 2019, volume: 9, edition: 5, DOI
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Dystrophin Deficiency Leads to Genomic Instability in Human Pluripotent Stem Cells via NO Synthase-Induced Oxidative Stress
Cells, year: 2019, volume: 8, edition: 1, DOI
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Freshwater Cyanotoxin Cylindrospermopsin Has Detrimental Stage-specific Effects on Hepatic Differentiation From Human Embryonic Stem Cells
Toxicological sciences, year: 2019, volume: 168, edition: 1, DOI
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Ligase 3-mediated end-joining maintains genome stability of human embryonic stem cells
Faseb Journal, year: 2019, volume: 33, edition: 6, DOI
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Non-invasive electromechanical cell-based biosensors for improved investigation of 3D cardiac models
Biosensors & bioelectronics : the international journal for the professional involved with research, technology and applications of biosensors and related devices, year: 2019, volume: 124, edition: JAN 15 2019, DOI
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The role of RNA Polymerase II contiguity and long-range interactions in the regulation of gene expression in human pluripotent stem cells.
Stem Cells International, year: 2019, volume: 2019, edition: Article ID 1375807, DOI
2018
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AFM Monitoring the Influence o f Selected Cryoprotectants on Regeneration of Cryopreserved Cells Mechanical Properties
Frontiers in Physiology, year: 2018, volume: 9, edition: 804, DOI
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Cryopreserved Cells Regeneration Monitored by Atomic Force Microscopy and Correlated With State of Cytoskeleton and Nuclear Membrane
IEEE TRANSACTIONS ON NANOBIOSCIENCE, year: 2018, volume: 17, edition: 4, DOI