Project information
Plasticity of Regulatory Mechanisms of the Central Nervous Systems
- Project Identification
- MSM141100001
- Project Period
- 1/1999 - 1/2004
- Investor / Pogramme / Project type
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Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Faculty of Medicine
- Keywords
- Plasticity; Regulatory Mechanisms; Central Nervous System; Preclinical and Clinical Aspects; Neurobiology; Neurophysiology; Neuroanatomy; Neuropharmacology; Clinical Neurology; Psychiatry; Regeneration Processes; Neurotransmitters; Epilepsy
The central nervous system, its neurobiological mechanisms and the possibilities of influencing them externally have become the subject of the BRAIN DECADE in the research strategy announced by president Bush and enacted in the USA in 1990, to which Europe joined in 1992. The intentions included into the project being submitted, i.e. the investigation of the neurobiological and neurophysiological mechanisms of the control of the motor and mental functions, of their abnormalities, and the possible therapeutic or preventive influencing of these are completely in line with the "Brain Decade" programme. The project a based on an integration of the of pre-clinical aspects of the research in neuroanatomy, neurophysiology, pharmacology, and clinical research in the clinical fields of neurology, neurosurgery, plastic surgery and psychiatry. 16 postgraduate students have been included into this faculty research.
Publications
Total number of publications: 700
1999
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Vliv imunostimulancií na průběh N-acetylace prokainamidu v izolovaných perfundovaných játrech potkana
Česká fyziologie, year: 1999, volume: 48, edition: 4
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Změny příjmu metamfetaminu v modelu "i. v. self-administration" u potkanů po premedikaci fluoxetinem
Neurobiologie duševních poruch, year: 1999
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Změny vegetativní regulace krevního tlaku u pacientů s vazodepresorickým typem neurokardiogenní synkopy
Cor et vasa, year: 1999, volume: 1999, edition: 4
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Zvýšení agresivity při vysazení diazepamu potlačuje premedikace isamoltanem (antagonista 5-HT1B receptorů)
Sborník abstrakt - 41. Psychofarmakologická konference Jeseník, year: 1999
1998
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Behavioural effects of 5-HT1A receptor ligands with different intrinsic activity in timid and aggresive singly-housed mice.
Behav. Pharmacol., year: 1998, volume: 9, edition: 1
1997
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Citalopram influence on phagocytosis of mouse leukocytes and its interaction with immunostimulatory effect of interferon-alfa
Homeostasis, year: 1997, volume: 38, edition: 1
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Concurrent treatment with verapamil suppresses immune and behavioural response to endogenous cannabinoid anandamide
Human Psychopharmacol., year: 1997, volume: 12, edition: 12
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Fluoxetine prevents behavioural signs of withdrawal from diazepam in the model of anxiety in mice
Abstract, International workshop on The Behavioural Pharmaco, year: 1997
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Látky vyvolávající závislost v interakci s jinými léčivy
Alkoholizmus a drogové závislosti, year: 1997, volume: 32, edition: 3
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Mice treated with the lower doses of tiapride response with the increased phagocytic activity of leukocytes
Naunyn-Schmiedebergs Arch. Pharmacol, year: 1997, volume: 356, edition: 4