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Project information
Development of a microfluidic system for the In vitro generation of retinal organoids.

Information

This project doesn't include Faculty of Arts. It includes Faculty of Medicine. Official project website can be found on muni.cz.
Project Identification
MUNI/IGA/1297/2021
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
  • Internal grant agency MU
MU Faculty or unit
Faculty of Medicine

Stem cell derived retinal organoids can serve as excellent models to study eye development and diseases. However, laborious formation of the organoids and missing control of cellular microenvironment leads to high heterogeneity of produced organoids. Here we propose to overcome these issues by combination of human pluripotent stem cells with microfluidic system to optimize conditions and factors that drive morphogenesis of retinal tissue in niche controlled over time and space.

Publications

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