Laser ablation Methods for Analysis of Urinary Stones: Comparison Study Based on Calibration Pellets

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Authors	NOVOTNÝ Karel ŠTĚPÁNKOVÁ Kateřina VAŠINOVÁ GALIOVÁ Michaela KANICKÝ Viktor KAISER Jozef HAHN David
Year of publication	2012
Type	Conference abstract
MU Faculty or unit	Central European Institute of Technology
Citation
Description	Methods based on laser ablation, such as Laser Induced Breakdown Spectroscopy (LIBS) and Laser Ablation Inductively Coupled Plasma Mass/Optical Emission Spectrometry (LA-ICP-MS/OES) are particularly suitable for urinary stones bulk and micro analysis. The aim of this study is to demonstrate the calibration capabilities and limitations of these techniques. There are no commercially available standards, which would correspond to urinary calculi matrix. Internal standardization is also difficult, mainly due to different crystalline phases in one kidney stone. Calibration pellets were prepared from human urinary stones with phosphate, oxalate and urate matrix. For this comparative study the most frequently used laser-ablation based analytical techniques were chosen, such as LIBS and LA-ICP-MS. Moreover some unconventional techniques such as simultaneous LIBS – LA-ICP-OES and laser ablation (LA) – LIBS were also utilized.
Related projects:	Utilization of the laser induced breakdown spectroscopy (LIBS) and laser ablation ICP-OES/MS spectroscopy for chemical mapping of biominerals CEITEC - Central European Institute of Technology