The Ecm11-Gmc2 Complex Promotes Synaptonemal Complex Formation through Assembly of Transverse Filaments in Budding Yeast

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Authors	HUMPHRYES Neil LEUNG Wing-Kit ARGUNHAN Bilge TERENTYEV Yaroslav DVOŘÁČKOVÁ Martina TSUBOUCHI Hideo
Year of publication	2013
Type	Article in Periodical
Magazine / Source	PLOS Genetic
MU Faculty or unit	Central European Institute of Technology
Citation
Doi	http://dx.doi.org/10.1371/journal.pgen.1003194
Field	Genetics and molecular biology
Keywords	MEIOTIC CHROMOSOME SYNAPSIS; MEIOSIS-SPECIFIC PROTEIN; DOUBLE-STRAND BREAK; SACCHAROMYCES-CEREVISIAE; ELEMENT PROTEIN; RECOMBINATION; SUMO; SEGREGATION; INITIATION; RED1
Description	Homologous chromosome pairing is one of the crutial step in meiotic division of gametes. Zip1 protein represents a key component during the formation of so-called synaptonemal complex (SC). Analysis of two Zip-related proteins from budding yeast S.cerevisiae revealed that Ecm11 and Gmc2 together with SUMO participate in reguation and correct function of Zip1 during SC assembly.
Related projects:	CEITEC - Central European Institute of Technology