Fluorescein Analogues as Photoremovable Protecting Groups Absorbing at 520 nm
| Authors | |
|---|---|
| Year of publication | 2013 |
| Type | Article in Periodical |
| Magazine / Source | Journal of Organic Chemistry |
| MU Faculty or unit | |
| Citation | |
| Web | http://pubs.acs.org/doi/abs/10.1021/jo301455n |
| Doi | http://dx.doi.org/10.1021/jo301455n |
| Field | Organic chemistry |
| Keywords | Photochemistry; protecting groups |
| Description | A new photoremovable protecting group, (6-hydroxy-3-oxo-3H-xanthen-9-yl)methyl (1), with a molar absorption coefficient epsilon of 4 x 104 m–1 cm–1 at 520 nm for the release of carboxylates or phosphates is reported. Three derivatives of 1 (diethyl phosphate, acetate, and bromide) were isolated as complexes with DDQ and shown to release the ligands with quantum yields 2.4% in aqueous solution. |
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