MALDI MS and SALD ICP MS: Complementary Detection Techniques for Metalloproteomics

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Authors

TOMALOVÁ Iva FOLTYNOVÁ Pavla KANICKÝ Viktor PREISLER Jan

Year of publication 2013
Type Article in Proceedings
Conference CECE Junior 2013
MU Faculty or unit

Central European Institute of Technology

Citation
Field Analytic chemistry
Keywords metalloproteomics; SALD ICP MS; MALDI MS
Description Matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) and substrate-assisted laser desorption inductively coupled plasma (SALD ICP) MS are proposed as complementary detection techniques that allows acquisition of both molecular and element specific information from a single capillary electrophoresis (CE) run recorded on a custom-designed sample target. The whole concept is demonstrated on the analysis of rabbit-liver metallothionein (MT) isoform mixture.
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