Image Analysis of Gene Locus Positions within Chromosome Territories in Human Lymphocytes

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Authors

ŠTĚPKA Karel FALK Martin

Year of publication 2014
Type Article in Proceedings
Conference Mathematical and Engineering Methods in Computer Science : Volume 8934 of the series Lecture Notes in Computer Science
MU Faculty or unit

Faculty of Informatics

Citation
Web http://link.springer.com/chapter/10.1007%2F978-3-319-14896-0_11
Doi http://dx.doi.org/10.1007/978-3-319-14896-0_11
Field Informatics
Keywords image analysis;fluorescence confocal microscopy;gene locus detection;chromosome territory
Description We presented a new image analysis method for determining in which part of a cell nucleus a gene locus is, in relation to its "parental" chromosome territory. The method is robust and does not rely on selecting an arbitrary threshold for the territory segmentation.
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