The influence of chronic application of olazapine on brain perfusion in rat
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| Year of publication | 2016 |
| Type | Conference abstract |
| MU Faculty or unit | |
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| Description | Olanzapin is a commonly used atypical antipsychotic drug. We hypothesize that long term therapy of olanzapin could alter region dependent blood brain perfusion, which we tested by arterial spin labeling (ASL) MR imaging. Statistical evaluation of the ASL results in the hippocampus, somatosensory cortex and piriform cortex revealed significantly lower somatosensory cortex perfusion in olanzapin-treated animals. |
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