Studium vlivu mědi na cytotoxicitu wedelolaktonu v buňkách karcinomu prsu pomocí (SALD) ICP MS
| Title in English | Study of copper effect on wedelolactone cytotoxicity in breast cancer cells by (SALD) ICP MS |
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| Authors | |
| Year of publication | 2017 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Performed experiments showed the subsequent cells treatment by Cu (II) and wedelolactone can significantly enhance the wedelolactone cytotoxicity. Considerable cytotoxicity increment was observed for cells with transfected hCtr1 gene. On the other hand, the simultaneous cells treatment led to reduction of wedelolactone cytotoxicty. This effect can be caused by Cu (II)-wed complex inability to penetrate through the cytoplasmic cell membrane. |
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