ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data

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Authors	BYSTRÝ Vojtěch REIGL Tomáš KREJČÍ Adam DEMKO Martin HANÁKOVÁ Barbora GRIONI Andrea KNECHT Henrik SCHLITT Max DREGER Peter SELLNER Leopold HERRMANN Dietrich PINGEON Marine BOUDJOGHRA Myriam RIJNTJES Jos POTT Christiane LANGERAK Anton W. GROENEN Patricia J. T. A. DAVI Frederic BRUGGEMANN Monika DARZENTAS Nikos
Year of publication	2017
Type	Article in Periodical
Magazine / Source	Bioinformatics
MU Faculty or unit	Central European Institute of Technology
Citation
Web	https://academic.oup.com/bioinformatics/article-abstract/33/3/435/2580414/ARResT-Interrogate-an-interactive-immunoprofiler?redirectedFrom=fulltext
Doi	http://dx.doi.org/10.1093/bioinformatics/btw634
Field	Biochemistry
Keywords	REPERTOIRE
Description	Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations.
Related projects:	CERIT Scientific Cloud Velká infrastruktura CESNET Encyklopedie CLL podskupin: unikátní znalostní databáze vybavená bioinformatickými nástroji použitelná v personalizované biomedicíně a klinické praxi CEITEC 2020