Cyclopropylamine plasma polymers for increased cell adhesion and growth
| Authors | |
|---|---|
| Year of publication | 2017 |
| Type | Article in Periodical |
| Magazine / Source | Plasma processes and polymers |
| MU Faculty or unit | |
| Citation | |
| Web | http://onlinelibrary.wiley.com/doi/10.1002/ppap.201600123/abstract;jsessionid=F73F366060DF262E0A74149729358262.f03t01 |
| Doi | http://dx.doi.org/10.1002/ppap.201600123 |
| Field | Plasma physics |
| Keywords | amine coatings; cell adhesion; cyclopropylamine; ESCA/XPS; pulsed discharges |
| Description | Plasma polymers with NHx groups were deposited from cyclopropylamine in low pressure radio frequency (RF) discharges. The amount of NHx decreased with increasing average power P-av, whereas the layer dissolution in water decreased and high P-av led to a slight film swelling. The C2C12 cells demonstrated very high adhesion to the layers regardless of the deposition conditions. Although the surface chemistry of amine-rich layers should enhance the cell proliferation, the WST-1 assay, and immunocytochemistry revealed lower cell proliferation and viability on the layers exhibiting above 18% of relative thickness loss in water. Promising results were obtained on the layers with better water stability and bearing 7-10% of NHx. |
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