Automated sample preparation for capillary electrophoresis-frontal analysis
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| Year of publication | 2017 |
| Type | Conference abstract |
| MU Faculty or unit | |
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| Description | The capillary electrophoresis-frontal analysis (CE-FA) is commonly used to determined drug-protein binding parameters in their native states without immobilization or labelling. Classical CE-FA sample preparation process uses off-line mixing reagents outside the capillary. On the other hand, as in the case of enzymatic or derivatization reaction, CE can uses electrophoretically mediated microanalysis (EMMA), where the sample is mixed directly in the capillary. This leads to the other advantages such as smaller sample consumption besides full automation. The main objective of this study was to test this methodological approach of sample preparation for CE-FA application. |
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