Serious chronic disease of the cervical spine and trauma in a young female from the middle ages (Czech Republic)

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Authors

KALOVÁ Kateřina BOBEROVÁ Kateřina PŘICHYSTALOVÁ Renáta NOVÁČEK Jan JAROŠOVÁ Ivana ZIKMUND Tomáš KAISER Jozef KYSELICOVÁ Klaudia ŠEBEST Lukáš BALDOVIČ Marián FRTUS Adam SIKORA Martin ALLENTOFT Morten E.

Year of publication 2019
Type Article in Periodical
Magazine / Source International Journal of Paleopathology
MU Faculty or unit

Faculty of Arts

Citation
Web https://www.sciencedirect.com/science/article/pii/S1879981717301559?via%3Dihub
Doi http://dx.doi.org/10.1016/j.ijpp.2018.11.004
Keywords Paleopathology; Tuberculosis; Osteomyelitis; Mycosis; Trauma; Fracture; Pohansko; Early middle ages
Description The skeletal remains of the young female (20–24 years) from Grave JP/106, discovered in the Southern Suburb of the Břeclav – Pohansko Stronghold (Early Middle Ages, 9th century-beginning of the 10th century, present day Czech Republic) display several noteworthy pathologies. The first is deformation of the mandible, which was most probably caused by a fracture of the ramus in combination with a subcondylar fracture. The spine of this young woman also exhibits a probable traumatic injury of the cervical spine in combination with a slowly growing structure situated inside the spinal canal, which caused deformation centered upon C7. The cervical and thoracic spine together with internal surfaces of several ribs exhibit infectious changes of advanced stage, in all likelihood of tuberculous origin, but osteomyelitis cannot be excluded. Histological analysis of the new bone formation in the ribs confirmed infectious origin, as does Micro CT of C5 and C6. Analyses conducted by two different departments with different methods (PCR amplification of 123 bp long section from IS6110 and Next Generation shotgun sequencing) failed to identify DNA of Mycobacterium tuberculosis from the first rib.
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