Automated family-wide annotation of secondary structure elements

This publication doesn't include Faculty of Arts. It includes Central European Institute of Technology. Official publication website can be found on muni.cz.

Authors

MIDLIK Adam HUTAŘOVÁ VAŘEKOVÁ Ivana HUTAŘ Jan MOTURU Tarakaramji NAVRÁTILOVÁ Veronika KOČA Jaroslav BERKA Karel SVOBODOVÁ VAŘEKOVÁ Radka

Type Chapter of a book
MU Faculty or unit

Central European Institute of Technology

Citation
Description Secondary structure elements (SSEs) are inherent parts of protein structures, and their arrangement is characteristic for each protein family. Therefore, annotation of SSEs can facilitate orientation in the vast number of homologous structures which is now available for many protein families. It also provides a way to identify and annotate the key regions, like active sites and channels, and subsequently answer the key research questions, such as understanding of molecular function and its variability. This chapter introduces the concept of SSE annotation and describes the workflow for obtaining SSE annotation for the members of a selected protein family using program SecStrAnnotator.
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