GLIOBLASTOMA SURVIVAL OUTCOMES RELATED TO CORTICAL/NEURAL STEM CELLS REGIONS

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Authors	KAZDA Tomáš JANČÁLEK Radim BELANOVÁ Renata POSPÍŠIL Petr BURKOŇ Petr HYNKOVÁ Ludmila ŠLAMPA Pavel LAKOMÝ Radek
Year of publication	2019
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	Subventricular brain zone (SVZ) and hippocampal regions are supposed to harbor astrocyte-like neural stem cells. While some tumors may arise from transformed SVZ stem cells, other may be initiated by neo-plastic transformation of non-SVZ progenitor cells or mature glial cells. Lim's et al classification (Neuro-Oncology 2007) of initial glioblastoma location, related to these neural stem cells regions, was predictive for invasive and multifocal tumor phenotype. The aim of this retrospective single-institutional study is to evaluate the relations of this Lim classification on survival parameters in unselected cohort of glioblastoma patients.
Related projects:	Reakce neuronální populace hipokampu na stereotaktickou radioterapii extratemporálních mozkových metastáz: vliv na neurokognitivní funkce a zachování kvality života