Association of the CD14 -260C/T polymorphism with plaque-induced gingivitis depends on the presence of Porphyromonas gingivalis
| Authors | |
|---|---|
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | International Journal of Paediatric Dentistry |
| MU Faculty or unit | |
| Citation | |
| web | https://onlinelibrary.wiley.com/doi/abs/10.1111/ipd.12847 |
| Doi | http://dx.doi.org/10.1111/ipd.12847 |
| Keywords | bacteria; CD14; gingivitis; polymorphism |
| Description | This study investigated the association between the functional polymorphism in the CD14 gene and the dental plaque microbiota in children with gingivitis.Gingivitis was detected in 64.2% of boys, but only in 35.8% of girls (P < .001). Children with gingivitis had a significantly higher occurrence of dental caries (P < .001). No significant differences in the CD14 -260C/T allele and genotype distribution among individuals with or without gingivitis in the whole cohort were found. Children with gingivitis and P gingivalis, however, were significantly more frequent carriers of the CT and TT genotypes than children with gingivitis without P gingivalis or healthy controls (P < .05). |
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