Synthesis of C-prenylated analogues of stilbenoid methyl ethers and their cyclic dihydrobenzopyranyl derivatives as potential anti-inflammatory agents

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Authors

PÍŽOVÁ Hana MALANÍK Milan ŠMEJKAL Karel ORAVEC Michal BOBÁĽ Pavel

Year of publication 2022
Type Article in Periodical
Magazine / Source RSC Advances
MU Faculty or unit

Faculty of Pharmacy

Citation
Web https://pubs.rsc.org/en/content/articlelanding/2022/RA/D2RA00441K
Doi http://dx.doi.org/10.1039/d2ra00441k
Keywords NATURAL STILBENOIDSVITIS-VINIFERAIN-VITRORESVERATROLDEMETHYLATIONINHIBITORSARYL
Description An efficient and versatile synthesis of the naturally occurring C-prenylated stilbenoid methyl ethers and their synthetic analogues is presented. The synthesis represents a six step convergent process including an optimised C-prenylation method. Furthermore, during the demethylation process, six new dihydro-benzopyranyl derivatives were obtained and isolated.
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