THE EFFECTS OF PLASMINOGEN ADDITION ON FIBRINOLYSIS WITH DIFFERENT r-tPA DOSES IN SYSTEMIC EMBOLISM RAT MODEL

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Authors

DAVUT AKSU Ahmet SCHEER Peter HLOŽKOVÁ Jana OPATŘILOVÁ Radka

Year of publication 2022
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Pharmacy

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Description Experimental outcomes demonstrated that the addition of PLG improves thrombolysis at both rtPA concentrations but non-significant in each group. In r-tPA 0,9/PLG8 group, lysis rate (mean value+-SD -0,5558 ± 0,1503) and AC shadow area change (mean value+-SD -32,33 ± 7,684) were significantly higher in 60 minute of protocol in comparison with r-tPA group.
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