THE EFFECTS OF PLASMINOGEN ADDITION ON FIBRINOLYSIS WITH  DIFFERENT r-tPA DOSES IN SYSTEMIC EMBOLISM RAT MODEL

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Authors	DAVUT AKSU Ahmet SCHEER Peter HLOŽKOVÁ Jana OPATŘILOVÁ Radka
Year of publication	2022
Type	Appeared in Conference without Proceedings
MU Faculty or unit	Faculty of Pharmacy
Citation
Attached files	Ahmet_Davut_Aksu_PHARM_MUNI_2022_abstract.pdf
Description	Experimental outcomes demonstrated that the addition of PLG improves thrombolysis at both rtPA concentrations but non-significant in each group. In r-tPA 0,9/PLG8 group, lysis rate (mean value+-SD -0,5558 ± 0,1503) and AC shadow area change (mean value+-SD -32,33 ± 7,684) were significantly higher in 60 minute of protocol in comparison with r-tPA group.
Related projects:	Biokompatibilní nanočástice jako cílené systémy pro dodávání léčiv a teranostik pro léčbu cévní mozkové příhody