LINEAR AND CONVERGENT SYNTHESIS OF HYDROXAMATE-BASED HISTONE DEACETYLASE INHIBITORS – A COMPARATIVE STUDIES

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Authors

ONUŠČÁKOVÁ Magdaléna PÍŽOVÁ Hana KAUEROVÁ Tereza KOLLÁR Peter BOBÁĽ Pavel

Year of publication 2022
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Pharmacy

Citation
Description Histone deacetylase inhibitors (HDACI) represent a relatively new generation of drugs with the ability to affect the expression of specific genes, which can repair controlled proliferation or damaged apoptotic processes in tumor cells. For this reason, HDACIs suggest a promising approach to cancer treatment.
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