Case report: radiation-induced lumbosacral plexopathy - a very late complication of radiotherapy for cervical cancer

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Authors

KRKOŠKA Peter KAZDA Tomáš VLAŽNÁ Daniela ADAMOVÁ Blanka

Year of publication 2022
Type Article in Periodical
Magazine / Source BMC Neurology
MU Faculty or unit

Faculty of Medicine

Citation
Web https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-022-03013-5
Doi http://dx.doi.org/10.1186/s12883-022-03013-5
Keywords Radiation-induced lumbosacral plexopathy; Lumbosacral plexus; Cervical cancer; Radiotherapy; Case report
Description Background: Lumbosacral plexopathy caused by radiotherapy is a rare but severe consequence of cancer treatment. This condition often leads to varying degrees of sensory and motor impairment. Neurological complications, which are typically permanent, manifest a long period after irradiation. Case presentation: We describe a case of progressive lower extremity weakness and sensory impairment in a woman who had been effectively treated with radiotherapy for cervical cancer with development 36 years after irradiation. The electrophysiological assessment revealed a subacute bilateral axonal lesion of the lumbosacral plexus. None of the clinical manifestations, serology, cerebrospinal fluid or imaging data discovered an explanation other than radiation-induced lumbosacral plexopathy (RILP). Conclusions: This case demonstrates that RILP may emerge more than 30 years after the radiotherapy.
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