Léčebné konopí a jeho význam pro současnou medicínu

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Title in English	Medical cannabis ad its significance for current medicine
Authors	LANDA Leoš JUŘICA Jan TROJAN Václav DEMLOVÁ Regina HŘIB Radovan
Year of publication	2023
Type	Article in Periodical
Magazine / Source	ANESTEZIOLOGIE A INTENZIVNI MEDICINA
MU Faculty or unit	Faculty of Medicine
Citation
Web	https://aimjournal.cz/artkey/aim-202301-0003_medical-cannabis-ad-its-significance-for-current-medicine.php
Doi	http://dx.doi.org/10.36290/aim.2023.003
Keywords	cannabis; THC; CBD; pain treatment
Attached files	Lecebne_konopi_a_jeho_vyznam_pro_soucasnou.pdf
Description	This review describes brief history of cannabis use and basic classification of substances found in the plant. It is focused on pharmacodynamics and pharmacokinetics of the main cannabinoids THC and CBD, with note on definition and significance of endocannabinoid system. Practically used routes of administration and drug dosage forms are mentioned as well. Furthermore, the article concisely summarizes specializations of physicians, who can prescribe medical cannabis, its main indications, adverse effects and contraindications, including aspect of safe driving in patients with this treatment. The last part of this review is aimed at therapy of pain and it brings two case reports of real patients treated with medical cannabis.