Prevalence kmenů Staphylococcus aureus produkujících Panton-Valentinův leukocidin izolovaných z ran

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Title in English Prevalence of Panton-Valentine leukocidin-producing Staphylococcus aureus strains isolated from wounds
Authors

HERMANOVÁ Laura Claudie BOTKA Tibor RŮŽIČKA Filip SIVÁKOVÁ Alena VRBSKÝ Jan

Year of publication 2023
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The aim of the study was to determine the prevalence of Staphylococcus aureus (STAU) strains producing Panton-Valentine leukocidin (PVL) toxin among STAU isolates from wounds of patients at the Microbiology Department of St. Anne's Hospital and the Faculty of Medicine of MUNI in the years 2021-2022. A total of 322 clinical isolates of STAU were collected and subsequently examined by PCR detection of lukS-PV and lukF-PV genes. Antibiotic susceptibility, patient age and wound location were also monitored. Seventeen PVL toxin producers were identified, thus the prevalence was 5.3% and the median age was 48 years. This result is comparable with similar studies from abroad. Among the strains, we only detected inducible MLSB resistance in one sample. However, there were few resistant isolates among the samples in the cohort (4% MRSA, 24% MLSB). Unfortunately, the majority of isolates with PVL-positive STAU did not have a wound location indicated. This work was supported by the programme project of the Ministry of Health of the Czech Republic with reg. no. NU21J05-00035.
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