Mimicking brain-tumor interactions using cerebral organoids and glioblastoma spheroids to study the migration of glioblastoma cells

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Authors

FEDOROVÁ Veronika SLOVÁČKOVÁ Jana AMRUZ ČERNÁ Kateřina POSPÍŠILOVÁ Veronika SEDMÍK Jiří CESNÁRIKOVÁ Soňa BARÁK Martin HENDRYCH Michal JANČÁLEK Radim BOHAČIAKOVÁ Dáša

Year of publication 2024
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Medicine

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Description Glioblastoma IDH-wildtype is the most aggressive and lethal form of brain tumor characterized by significant heterogeneity and a poor prognosis. To advance treatment strategies, better models that replicate the in vivo behavior of glioblastoma cells are essential. Such an in vitro model can then be used to study mechanisms of therapeutic resistance and screening of new drugs against glioblastoma multiforme.
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