Microwave Application in 1,3-Dipolar Cycloadditions and Their Influence upon Formation of either 1,3-Oxazolidines or Pyrrolidines
| Authors | |
|---|---|
| Year of publication | 2000 |
| Type | Article in Proceedings |
| Conference | Proceedings - International Conference on Microwave Chemistry |
| MU Faculty or unit | |
| Citation | |
| Field | Organic chemistry |
| Description | A way to preparation of ethyl-N-alkyl-3,4-disubstituted pyrrolidine-2-carboxylates by the reaction of azomethine ylide and dipolarophile under microwave irradiation was searched. The ylide was generated in situ by the reaction of ethyl-N-alkylaminoacetates with paraformaldehyde. Fumaronitrile and dimethylfumarate were used as dipolarophiles. Comparison of reaction in toluene and under solventless conditions as well as influence of a solid support was searched. |
| Related projects: |