Alkoholizmus a interleukin 6
| Title in English | Alcoholism and IL-6 |
|---|---|
| Authors | |
| Year of publication | 2001 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | IL-6 alcoholism association polymorphism |
| Description | Cytokines play the important role in the CNS in the modulations of dopaminergic, serotonergic, noradrenergic and cholinergic systems. From this point of view, the gene for IL-6 is a possible candidate gene of the dispositions to the alcohol dependence. We investigated the relationship between the G/C -174 polymorphism of the IL-6 gene and alcohol dependence in 121 alcoholics and 84 control subjects. No significant difference in allele frequencies between alcoholic group and control group was found for this polymorphic site. |
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