Alkoholizmus a interleukin 6

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Title in English Alcoholism and IL-6
Authors

ŠERÝ Omar HLADILOVÁ Renáta HŘÍBKOVÁ Hana HLOUŠKOVÁ Renáta NOVOTNÝ Miroslav ZVOLSKÝ Petr

Year of publication 2001
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Faculty of Science

Citation
Field Physiology
Keywords IL-6 alcoholism association polymorphism
Description Cytokines play the important role in the CNS in the modulations of dopaminergic, serotonergic, noradrenergic and cholinergic systems. From this point of view, the gene for IL-6 is a possible candidate gene of the dispositions to the alcohol dependence. We investigated the relationship between the G/C -174 polymorphism of the IL-6 gene and alcohol dependence in 121 alcoholics and 84 control subjects. No significant difference in allele frequencies between alcoholic group and control group was found for this polymorphic site.
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