Can we predict the hemodynamical effect of malignant arrhythmias from the endothelin-1 gene polymorphism?

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Authors

KOZÁK Milan KŘIVAN Lubomír IZAKOVIČOVÁ HOLLÁ Lydie SEMRÁD Bořivoj VAŠKŮ Anna VÁCHA Jiří

Year of publication 2001
Type Article in Periodical
Magazine / Source Europace (European Pacing, Arrhythmias and Cardiac Electrophysiology
MU Faculty or unit

Faculty of Medicine

Citation
Field Cardiovascular diseases incl. cardiosurgery
Description Endothelin-1 (ET-1)is known to facilitate ventricular arrhythmias. The aim was to investigate the frequency distribution of the common polymorphism of ET-1 gene and its possible relation to states leading to hemo-dynamical colaps during malignant ventricular arrhythmias (MVA) in ICD patients.
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