One-pot Synthesis of N1-(2-Phenyl-4-quinazolinyl)-2--R-1-hydrazinecarbothioamide
| Authors | |
|---|---|
| Year of publication | 2001 |
| Type | Article in Proceedings |
| Conference | Sborník príspevkov 53. zjazd Chemických spoločností |
| MU Faculty or unit | |
| Citation | |
| Field | Organic chemistry |
| Keywords | Quinazolines; hydrazines; azomethines; enamines |
| Description | The key intermediate N2-(2-cyanophenyl)-N1-thioxo-methylidenebenzene-1-carboximidamide 1 reacts in acetonitrile with N,N-disubstituted hydrazine derivatives to afford N1-(2-phenyl-4-quinazolinyl)-2,2-di-R-1-hydrazinecarbothioamide 4. On the other hand the reaction of 1 with hydrazine in acetone give N1-(2-phenyl-3,4-dihydroquinazolin-4-yliden)-1-isopropenyl-2-(1-methylethylidene)hydrazine-1-carbothioamide. |
| Related projects: |