Asociace polymorfismů M235T a G(-6)A v genu pro angiotenzinogen s chronickým srdečním selháním

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Title in English	Association of angiotensinogen gene M235T and G(-6)A polymorphisms with chronic heart failure
Authors	GOLDBERGOVÁ Monika ŠPINAROVÁ Lenka ŠPINAR Jindřich VAŠKŮ Anna
Year of publication	2002
Type	Article in Periodical
Magazine / Source	Chemické listy
MU Faculty or unit	Faculty of Medicine
Citation
Field	Genetics and molecular biology
Keywords	angiotensinogen; polymorphism; chronic heart failure
Description	The aim of the study was to focus on relationship between the angiotensinogen (AGT) gene polymorphisms, M235T and promoter G(-6)A, and chronic heart failure in the Czech population. 158 patients with chronic heart failure (functional class NYHA II-IV, ejection fraction <40% cardiothoracic index >50%) were compared with control group of 200 subjects of similar age and sex distribution, without any personal history of cardiovascular diseases
Related projects:	Molecular pathophysiology of multigene diseases