Relation between sexual dysfunctions and CYP 2D6 activity
| Authors | |
|---|---|
| Year of publication | 2002 |
| Type | Article in Periodical |
| Magazine / Source | European psychiatry |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | depressive disorder; paroxetine; sexual dysfunctions; CYP 2D6 genotype; CYP 2D6 phenotype |
| Description | The frequency and severity of adverse effects related to sex-life were studied in patients with depressive disorder in relationship with their CYP2D6 genotype/phenotype. Subjects in which the CYP 2D6 capacity was decreased due to the long-term paroxetine treatment reported significantly higher occurence of sexual dysfunction as evaluated by the ASEX scale. |
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