Vliv farmakologické manipulace s 5-HT1A receptorovým podtypem na sociální chování myší

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Title in English	Influence of pharmacological manipulation with 5-HT1A receptor subtype on social behaviour in mice
Authors	NOVÁKOVÁ Jana VINKLEROVÁ Jana ŠULCOVÁ Alexandra
Year of publication	2002
Type	Article in Periodical
Magazine / Source	Psychiatrie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	5-HT1A receptor subtype; social behaviour; mice
Description	The present study investigated the influence of ligand of 5-HT1A receptor ligand S 15535 which acts as an agonist and an antagonist at presynaptic and postsynaptic sites respectively, on agonistic behaviour in mice. In conclusion, S 15535 exerted marked antiaggressive action in aggressive mice with less pronounced effect on defensive-ascape behaviour in timid animals.
Related projects:	Plasticity of Regulatory Mechanisms of the Central Nervous Systems