Negativní příznaky a nová atypická antipsychotika
| Title in English | Negative symptoms and new atypical antipsychotics |
|---|---|
| Authors | |
| Year of publication | 2002 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | schizophrenia; negative symptoms; atypical antipsychotics; amisulpride; ziprasidone |
| Description | Importance and classification of negative symptoms and their control by treatment are summarized. Recently, more strict criteria for studies concerning efficacy of antipsychotics on negative symptoms are required. These more strict criteria were met in studies with two atypical antipsychotics, which were launched in the Czech Republic recently, i.e. amisulpiride (Solian) and ziprasidone (Zeldox). Double-blind, placebo controlled studies focused on čefficacy in negative symptoms are described in more detail. In both studies the active substances were significantly better than placebo. Whether the positive results on negative symptoms will be sufficient for thereintegration of patientes with schizophrenia into society will be apparent in the future. |
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