Interleukin-18 gene promoter polymorphisms and IgE-mediated allergy in Czech population

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Authors	SCHÜLLER Marcel IZAKOVIČOVÁ HOLLÁ Lydie RYBNÍČEK Ondřej BUČKOVÁ Dana VÁCHA Jiří
Year of publication	2003
Type	Article in Periodical
Magazine / Source	Allergy
MU Faculty or unit	Faculty of Medicine
Citation
Field	Genetics and molecular biology
Keywords	allergy polymorphism interleukin-18
Description	Here we present no direct association of the -607C/A and -137G/C polymorphisms in the IL-18 gene promoter with IgE-mediated allergic diseases or total IgE serum level in the Czech population. However, -607A allele was significantly associated positive skin prick test reactivity to Alternaria.
Related projects:	Molecular pathophysiology of multigene diseases