Involvement of 5-HT1 and 5-HT2 receptor in regulation of methamphetamine self-admininstration in rats
| Authors | |
|---|---|
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | European Neuropsychopharmacology |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | 5-HT1 and 5-HT2 receptor ligands; methamphetamine; self-administration;rats |
| Description | Present work brings new aspects into the understanding of methamphetamine addiction studying the role of two different serotonergic receptor subtypes 5-HT1 and 5-HT2. According to our results, the most important inhibitory influence for the conditioned reward responding to methamphetamine i.v. self-administration showed pharmacological agonistic manipulation of the 5-HT1B receptor subtype. |
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