Problematika neurologických měkkých příznaků a schizofrenie
| Title in English | Neurological soft signs in schizophrenia |
|---|---|
| Authors | |
| Year of publication | 2003 |
| Type | Article in Periodical |
| Magazine / Source | Psychiatrie časopis pro moderní psychiatrii |
| MU Faculty or unit | |
| Citation | |
| Field | Psychiatry, sexuology |
| Keywords | soft signs; shcizophrenia; first-episode schizophrenia; risperidone |
| Description | Research on soft signs in shcizophrenia is briefly reviewed. Further own resultsfound in males hospitalized for the first time with the diagnosis of first-episode schizophrenia are presented. The neurological soft signs were evaluated using the Neurological Evaluation Scale (n=90)during acute treatment and after one year (n=50). Soft signs were present in 66 (73%) of the 90 schizophrenic patients (defined as one NES item rated 2). In 2/4 component scores (motor coordination and motor sequencing) a significant decrease after 1 year in relation to values in acute treatment was observed. In a small sample of patientes succesfully treated only with risperidone no significant changes were found. Soft signs are evident only in a subgroup of patientes, which is consistent with the idea, that schizophrenia represents a heterogenous disorder. |
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