Molecular dynamics simulations of RNA kissing loop motifs reveal structural dynamics and formation of cation-binding pockets

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Authors	RÉBLOVÁ Kamila ŠPAČKOVÁ Naděžda ŠPONER Judit KOČA Jaroslav ŠPONER Jiři
Year of publication	2003
Type	Article in Periodical
Magazine / Source	Nucleic Acids Research
MU Faculty or unit	Faculty of Science
Citation
Field	Biophysics
Keywords	RNA; kissing loop motifs; molecular dynamics; cation-binding pockets
Description	Loop-loop interactions between RNA hairpins represent an important class of RNA-RNA recognition motifs. These `kissing-loop' complexes participate in antisense regulation of a variety of cellular processes in prokaryotic cells and in bacteriophages. To under-stand the function of kissing complexes, we have carried out molecular dynamics simulations on two types of RNA kissing structures.
Related projects:	Biomolecular Center