K teorii senzitizace u látek vyvolávajících závislost
Title in English | Drugs of abuse sensitization theory |
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Authors | |
Year of publication | 2004 |
Type | Article in Periodical |
Magazine / Source | Adiktologie |
MU Faculty or unit | |
Citation | |
Field | Pharmacology and pharmaceutical chemistry |
Keywords | behavioural sensitization-drug dependence-dopamine |
Description | The study presented brings a summarized view to the behavioural sensitization phenomenon frequently referred coherently with drug dependence. There are circumscribed both sensitization and tolerance which used to be often associated with drug dependence. Furthermore, terminological notes concerning to sensitization are explained and its neurobiological basis is outlined, especially pharmacodynamic changes which can underlie sensitization. Particularly, attention is focused on the changes of dopaminergic neurotransmitter system plasticity. |
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