Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis

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Authors

IZAKOVIČOVÁ HOLLÁ Lydie FASSMANN Antonín VAŠKŮ Anna PÁVKOVÁ GOLDBERGOVÁ Monika BERÁNEK Michal ZNOJIL Vladimír VANĚK Jiří VÁCHA Jiří

Year of publication 2005
Type Article in Periodical
Magazine / Source J Periodontol
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords gelatinase A; MMP-2; gene; polymorphism; haplotype; periodontitis
Description Gelatinase A (matrix metalloproteinase-2, MMP-2) has been shown to play an important role in the pathogenesis of several disorders, including periodontal diseases. In this study, we test the hypothesis that variations in this gene influence the development and severity of chronic periodontitis.
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