Association of variants in angiotensin-converting enzyme and endothelin-1 genes with phototherapy in cutaneous T-cell lymphoma

• Authors: VAŠKŮ Vladimír; VAŠKŮ Julie; PÁVKOVÁ GOLDBERGOVÁ Monika; VAŠKŮ Anna
• Year of publication: 2004
• Type: Article in Periodical
• Magazine / Source: Acta dermatovenerologica
• MU Faculty or unit: Faculty of Medicine
• Field: Dermatovenerology
• Keywords: I/D ACE; endothelin-1; gene; polymorphism;mycosis fungoides
• Description: The cutaneous T-cell lymphoma (CTCL) is a disease characterised by cutaneous infiltrates of malignant, clonally expanded T-cells. Because individual genetic determination of angiogenetic and antioxidant properties of blood vessels could be partly responsible for phototherapy in CTCL patients, three polymorphisms in angiotensin converting enzyme and endothelin-1 genes were determined.

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