Association of the Cluster of Genetic Risk Factors in Loci Related to Glycoxidation with Diabetic Nephropathy in Type 2 Diabetes Mellitus

Warning

This publication doesn't include Faculty of Arts. It includes Faculty of Medicine. Official publication website can be found on muni.cz.

Authors	KAŇKOVÁ Kateřina STEJSKALOVÁ Andrea PÁCAL Lukáš HERTLOVÁ Miluše KRUSOVÁ Darja
Year of publication	2005
Type	Conference abstract
MU Faculty or unit	Faculty of Medicine
Citation
Description	We found significant association of selected genetic variants in the RAGE, SOD2 and PARP-1 genes with the presence of DN in type 2 diabetics and, in the case of RAGE and PARP-1, also with acceleration of DN onset. We therefore conclude that those htSNPs could be regarded disease markers of DN.
Related projects:	Relationship between genetic variability of antioxidant system and late complications of diabetes mellitus Molecular pathophysiology of multigene diseases